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Scaffold 1-phenylpyrrolidin-2-one

1-phenylpyrrolidin-2-one

These 1-phenylpyrrolidin-2-one analogues were selected by Bemis-Murcko Loose Framework method. There are 387 analogues of this scaffold available for sale as building blocks.

Analogues

4-(2-oxopyrrolidin-1-yl)benzohydrazide View
1-[2-(butan-2-yl)phenyl]-5-oxopyrrolidine-3-carboxylic acid View
1-[3-(methylsulfanyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid View
1-(2-methoxy-5-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-(5-chloro-2,4-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-[4-(diethylsulfamoyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid View
2-{[4-(2-oxopyrrolidin-1-yl)phenyl]formamido}acetic acid View
4-chloro-3-(2-oxopyrrolidin-1-yl)benzoic acid View
1-(4-acetylphenyl)pyrrolidin-2-one View
2-(2-oxopyrrolidin-1-yl)benzoic acid View
2-[4-(2-oxopyrrolidin-1-yl)phenyl]acetic acid View
1-(2-aminophenyl)pyrrolidin-2-one View
1-[4-(2-bromoacetyl)phenyl]pyrrolidin-2-one View
1-(3-acetylphenyl)pyrrolidin-2-one View
4-chloro-2-(2-oxopyrrolidin-1-yl)benzoic acid View
4-(2-oxopyrrolidin-1-yl)benzonitrile View
2-[3-(2-oxopyrrolidin-1-yl)phenoxy]acetic acid View
2-[4-(2-oxopyrrolidin-1-yl)benzenesulfonamido]acetic acid View
2-[4-(2-oxopyrrolidin-1-yl)phenoxy]acetic acid View
3-chloro-N-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide View
1-[3-(2-bromoacetyl)phenyl]pyrrolidin-2-one View
2-chloro-N-[4-(2-oxopyrrolidin-1-yl)phenyl]acetamide View
2-chloro-N-[2-(2-oxopyrrolidin-1-yl)phenyl]acetamide View
2-chloro-N-[3-(2-oxopyrrolidin-1-yl)phenyl]acetamide View
(2E)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]prop-2-enoic acid View
1-(4-amino-2-chlorophenyl)pyrrolidin-2-one View
1-(4-amino-2-methoxyphenyl)pyrrolidin-2-one View
1-[4-(2-chloroacetyl)phenyl]pyrrolidin-2-one View
1-(2,4-difluorophenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-(3-ethylphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid View
5-oxo-1-[3-(propan-2-yl)phenyl]pyrrolidine-3-carboxylic acid View
1-(2-fluoro-4-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-(2-bromophenyl)-5-oxopyrrolidine-3-carboxylic acid View
5-oxo-1-(4-propylphenyl)pyrrolidine-3-carboxylic acid View
4-amino-1-(2-fluorophenyl)pyrrolidin-2-one View
4-amino-1-(4-fluorophenyl)pyrrolidin-2-one View
4-amino-1-(4-methoxyphenyl)pyrrolidin-2-one View
1-[3-(aminomethyl)phenyl]pyrrolidin-2-one View
1-(4-methyl-3-nitrophenyl)pyrrolidin-2-one View
ethyl 4-(2-oxopyrrolidin-1-yl)benzoate View
1-[3-methyl-4-(propan-2-yl)phenyl]-5-oxopyrrolidine-3-carboxylic acid View
1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carbohydrazide View
5-oxo-1-phenylpyrrolidine-3-carbohydrazide View
1-(4-fluorophenyl)-5-oxopyrrolidine-3-carbohydrazide View
1-(4-acetylphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-(4-carbamoylphenyl)-5-oxopyrrolidine-3-carboxylic acid View
1-(4-methylphenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3,4-dimethylphenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3,5-dimethylphenyl)-2-oxopyrrolidine-3-carboxylic acid View
2-oxo-1-[4-(propan-2-yl)phenyl]pyrrolidine-3-carboxylic acid View
1-(4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3-chlorophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(2-bromophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3-bromophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(4-bromo-2-methylphenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(3,4-dichlorophenyl)-2-oxopyrrolidine-3-carboxylic acid View
1-(2,5-dichlorophenyl)-2-oxopyrrolidine-3-carboxylic acid View