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Scaffold 2-(pyridin-4-yl)pyrimidine

These 2-(pyridin-4-yl)pyrimidine analogues were selected by Bemis-Murcko Loose Framework method. There are 22 analogues of this scaffold available for sale as building blocks.

Analogues

2-(pyridin-4-yl)pyrimidine-5-carboxylic acid View

5,6-dimethyl-2-(pyridin-4-yl)pyrimidin-4-ol View

2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidin-4-ol View

2-(pyridin-4-yl)pyrimidin-4-amine View

N-methyl-5-nitro-2-(pyridin-4-yl)pyrimidin-4-amine View

6-methyl-2-(pyridin-4-yl)pyrimidin-4-ol View

3-chloro-2,2-dimethyl-N-[2-(pyridin-4-yl)pyrimidin-4-yl]propanamide View

4-chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine View

6-(methoxymethyl)-2-(pyridin-4-yl)pyrimidin-4-ol View

4-chloro-6-methyl-2-(pyridin-4-yl)pyrimidine View

4,5-dichloro-6-methyl-2-(pyridin-4-yl)pyrimidine View

4-chloro-6-ethyl-2-(pyridin-4-yl)pyrimidine View

4-chloro-5,6-dimethyl-2-(pyridin-4-yl)pyrimidine View

5-methoxy-2-(pyridin-4-yl)pyrimidin-4-ol View

4-chloro-5-methoxy-2-(pyridin-4-yl)pyrimidine View

4-hydrazinyl-5,6-dimethyl-2-(pyridin-4-yl)pyrimidine View

ethyl 4-chloro-2-(pyridin-4-yl)pyrimidine-5-carboxylate View

ethyl 4-hydroxy-2-(pyridin-4-yl)pyrimidine-5-carboxylate View

4-hydrazinyl-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine View

5-bromo-2-(pyridin-4-yl)pyrimidine View

5-bromo-2-(pyridin-4-yl)pyrimidin-4-amine View

4-(dimethoxymethyl)-2-(pyridin-4-yl)pyrimidine View

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