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Scaffold 4-methylidene-2-phenylpyrazol-3-one

These 4-methylidene-2-phenylpyrazol-3-one analogues were selected by Bemis-Murcko Loose Framework method. There are 11 analogues of this scaffold available for sale as building blocks.

Analogues

(4Z)-4-[(dimethylamino)methylidene]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one View

(4Z)-4-[(dimethylamino)methylidene]-3-methyl-1-(4-nitrophenyl)-4,5-dihydro-1H-pyrazol-5-one View

methyl 2-[(4Z)-4-[(dimethylamino)methylidene]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]acetate View

methyl 2-({[(4Z)-5-oxo-1-phenyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}amino)acetate View

methyl 2-({[(4Z)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}amino)acetate View

methyl (2E)-3-(dimethylamino)-2-[(4Z)-4-[(dimethylamino)methylidene]-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]prop-2-enoate View

1-(4-bromophenyl)-4-[(hydroxyamino)methylidene]-3-methyl-4,5-dihydro-1H-pyrazol-5-one View

ethyl (2Z)-3-(dimethylamino)-2-[(4Z)-4-[(dimethylamino)methylidene]-1-(4-methoxyphenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]prop-2-enoate View

methyl 2-[(4Z)-4-[(dimethylamino)methylidene]-1-(4-methoxyphenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetate View

methyl (2E)-3-(dimethylamino)-2-[(4Z)-4-[(dimethylamino)methylidene]-1-(4-methoxyphenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]prop-2-enoate View

3-tert-butyl-4-(chloromethylidene)-1-phenyl-4,5-dihydro-1H-pyrazol-5-one View

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